Recent Articles

Ras–dependent Paracrine Cascades

| August 17, 2017 | 0 Comments

Ras–dependent Paracrine Cascades Most pancreatic cancers are driven by mutant K-Ras genes, and comprise a minority of cancer cells in a densely fibrotic and highly secretory tumor microenvironment. Interrupting the paracrine cascades in pancreatic cancers may improve treatment.See Original Article

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FDA Approves Nivolumab for Some Metastatic Colorectal Cancers

| August 17, 2017 | 0 Comments

FDA Approves Nivolumab for Some Metastatic Colorectal Cancers FDA has granted accelerated approval to the immunotherapy drug nivolumab (Opdivo®) for patients with metastatic colorectal cancer whose tumors have alterations that affect DNA repair.See Original Article

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Study Uncovers Previously Unrecognized Effect of Chemotherapy

| August 15, 2017 | 0 Comments

Study Uncovers Previously Unrecognized Effect of Chemotherapy A new study conducted primarily in mice suggests that chemotherapy given before surgery for breast cancer can cause changes in cells in and around the tumor that are tied to an increased risk of the cancer spreading to other areas of the body.See Original Article

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Ibrutinib Becomes First FDA-Approved Drug for Chronic Graft-Versus-Host Disease

| August 11, 2017 | 0 Comments

Ibrutinib Becomes First FDA-Approved Drug for Chronic Graft-Versus-Host Disease A drug used to treat several blood cancers, ibrutinib, has been approved by FDA to treat chronic graft-versus-host disease, making it the first approved therapy for this potentially fatal side effect of cancer-related stem cell transplants.See Original Article

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Dual-Biomarker Blood Test Shows Promise for Pancreatic Cancer Early Detection

| August 9, 2017 | 0 Comments

Dual-Biomarker Blood Test Shows Promise for Pancreatic Cancer Early Detection A new blood test that measures levels of two specific proteins may be able to accurately detect pancreatic cancer at its earliest stages, when it is most likely to respond to treatment, findings from a new study suggest. See Original Article Grantee Spotlight: Daniel Petereit, […]

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October Spotlight: Breast Cancer Disparity Highlights

| August 9, 2017 | 0 Comments

October Spotlight: Breast Cancer Disparity Highlights CRCHD recognizes Breast Cancer Awareness Month by highlighting breast cancer-related disparities and CRCHD grantees.See Original Article Special Spotlight: Levi A. Garraway, M.D., Ph.D., Receives Prestigious Jane Cooke Wright Award from American Association for Cancer Research Dr. Levi A. Garraway, a former CRCHD CURE trainee, received the prestigious Jane Cooke […]

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Ras Mitogenic Signaling: p53 Enters the Stage

| August 8, 2017 | 0 Comments

Ras Mitogenic Signaling: p53 Enters the Stage Mariano Barbacid and Matthias Drosten describe experiments that reveal a new role for the p53/p21Clp1/Rb axis in controling MAPK signaling.See Original Article Grantee Spotlight: Shawna Hudson, Ph.D. – Helping Cancer Survivors EXCEL Dr. Shawna Hudson, an NCI/CRCHD K01 awardee, works to ensure cancer survivors continue to stay in […]

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Adolescents Who Wouldn’t Have Smoked May Be Drawn to E-Cigarettes

| August 8, 2017 | 0 Comments

Adolescents Who Wouldn’t Have Smoked May Be Drawn to E-Cigarettes The findings from a recent study suggest that adolescents are not just using e-cigarettes as a substitute for conventional cigarettes but that e-cigarettes are attracting new users to tobacco products.See Original Article A Holistic Approach to Cancer Health Disparities Recognizing that complex factors underlie health […]

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“First in Human” Documentary Highlights NCI Immunotherapy Research

| August 7, 2017 | 0 Comments

“First in Human” Documentary Highlights NCI Immunotherapy Research The Discovery Channel special, First in Human, will feature some of the groundbreaking work on cancer immunotherapy being done at the NIH Clinical Center, including CAR T-cell therapy and TIL therapy.See Original Article Most American Adults Do Not Use Sunscreen Regularly The majority of Americans are not […]

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In Melanoma, Personalized Treatment Vaccines Show Promise

| August 4, 2017 | 0 Comments

In Melanoma, Personalized Treatment Vaccines Show Promise Results of an early-phase trial showed that a treatment vaccine personalized to a specific patient’s cancer generated a robust immune response against the cancer and may have helped to prevent it from returning.See Original Article

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