Recent Articles

Ras: Do We Know Its Structure Well Enough?

| May 11, 2017 | 0 Comments

Ras: Do We Know Its Structure Well Enough? Carla Mattos discusses how subtle changes in distant parts of RAS molecules may influence the conversion of GTP to GDP that is fundamental to RAS signaling.See Original Article Special Spotlight: 2014 AACR Conference: The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved A […]

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Special Spotlight: In Memoriam Patricia Susana Lorenzo, Ph.D. Cancer Researcher and Former CRCHD Grantee

| May 11, 2017 | 0 Comments

Special Spotlight: In Memoriam Patricia Susana Lorenzo, Ph.D. Cancer Researcher and Former CRCHD Grantee CRCHD celebrates the life and work of Dr. Patricia Susana Lorenzo, a compassionate woman, friend, colleague, wife, and dedicated researcher.See Original Article Message from Dr. Lowy A message from NCI Acting Director, Douglas Lowy, about the progress of the RAS Initiative […]

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RAS Pathway v2.0

| May 10, 2017 | 0 Comments

RAS Pathway v2.0 Frank McCormick, scientific lead of the RAS Initiative, incorporates over 30 suggestions from the RAS community to formulate an updated version of the RAS pathway, v2.0See Original Article Special Spotlight: World Cancer Day – Ending Cancer Health Disparities is Not Beyond Us CRCHD observes World Cancer Day 2015, joining the global fight […]

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Collection of Patient-Reported Outcomes Feasible in Cancer Clinical Trials

| May 10, 2017 | 0 Comments

Collection of Patient-Reported Outcomes Feasible in Cancer Clinical Trials Cancer patients, even those who are undergoing difficult treatments, are willing to devote time to completing thorough assessments of the side effects they encounter in clinical trials, a new study finds.See Original Article Grantee Spotlight: Nathan Ellis, Ph.D. Seeks Molecular Basis of Colorectal Cancer Disparities in […]

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The Mutational Spectra of Cancer Genes in TCGA Data

| May 10, 2017 | 0 Comments

The Mutational Spectra of Cancer Genes in TCGA Data The Cancer Genome Atlas has catalogued mutations in more than 30 cancer types. The NCI RAS Initiative uses TCGA data to prioritize and inform its research objectives. The bar graphs show data for KRAS, HRAS, NRAS, BRAF, TP53, EGFR, PIK3CA, and PTEN.See Original Article Grantee Spotlight: […]

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Study Finds Storytelling Helps Overcome Cervical Cancer Screening Disparities

| May 9, 2017 | 0 Comments

Study Finds Storytelling Helps Overcome Cervical Cancer Screening Disparities Using a storytelling approach to educate women about cervical cancer screening eliminated disparities in attitudes toward screening and behavior, according to a new study.See Original Article Adolescents Who Wouldn’t Have Smoked May Be Drawn to E-Cigarettes The findings from a recent study suggest that adolescents are […]

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Advancing Cancer Care Delivery Research in the Next Decade

| May 9, 2017 | 0 Comments

Advancing Cancer Care Delivery Research in the Next Decade A more substantial and coordinated effort is needed to advance the science of cancer care delivery to help address the complex problems facing our health care systems. In response, NCI has created a new Healthcare Delivery Research Program (HDRP) to strengthen its support and coordination of […]

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Looking to the Future of Childhood Cancer Research

| May 9, 2017 | 0 Comments

Looking to the Future of Childhood Cancer Research NCI’s Dr. Malcolm Smith discusses future directions of childhood cancer research, including treatment directions and clinical trials.See Original Article Cancer Currents Now Available in Spanish As part of our effort to more effectively reach patients, health care providers, and researchers with timely, authoritative, and scientifically accurate cancer […]

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FDA Approves Combination Drug for Patients with Advanced Colorectal Cancer

| May 9, 2017 | 0 Comments

FDA Approves Combination Drug for Patients with Advanced Colorectal Cancer The FDA has approved a single drug that combines trifluridine and tipiracil to treat patients with metastatic colorectal cancer whose disease progressed after standard treatment. See Original Article FDA Approves Expanded Indication for Carfilzomib in Patients with Multiple Myeloma The FDA has approved carfilzomib in […]

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Novel Treatment Approach Shrinks Ovarian Tumors in Mice

| May 9, 2017 | 0 Comments

Novel Treatment Approach Shrinks Ovarian Tumors in Mice Researchers have developed a new approach for treating tumors that express mutant versions of the p53 protein, which are present in more than half of all cancers, including an aggressive and common subtype of ovarian cancer.See Original Article Who Will Respond to PD-1 Inhibition? Study Provides Clues […]

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